What to Know About Targeted Therapy for Breast Cancer

The Goal of Targeted Therapy for Breast Cancer

A new type of treatment may be used for breast cancer. It’s called targeted therapy. It uses molecularly targeted drugs. That means the drugs zone in on the exact change in the cell that lets cancer cells grow and spread. There’s a specific kind of targeted drug for breast cancer. These drugs are called monoclonal antibodies. They work by stopping or slowing the growth of a certain protein in cancer cells. For breast cancer, the drug is Herceptin (trastuzumab). Herceptin aims for a protein called HER-2 or erb B2. That stands for human epidermal growth factor receptor-2. About 20 to 30% of breast cancer tumors make too much of this protein. This is called over expression. These tumors tend to grow faster than tumors that don’t make too much HER-2. And these tumors are more likely to recur. Treatment with Herceptin can stop or slow the growth of cancer cells.